Health Condition 1: G968- Other specified disorders of central nervous system
Conditions
Interventions
Intervention1: Intravenous Caffeine: Single dose of caffeine citrate at 20mg/kg between 36 to 50 hours of life given via the intravenous route of administration
Control Intervention1: Nil: Nil
Sponsors
Reema Garegrat
Eligibility
Inclusion criteria
Inclusion criteria: All male and female newborns with hypoxic ischemic encephalopathy till 30 days of life
Exclusion criteria
Exclusion criteria: No sex is excluded. Age beyond 30 days is excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in cerebral oxygenation pre and post caffeine administrationTimepoint: Change in cerebral oxygenation pre and post caffeine administration between 36 to 50 hours of life only. Baseline 2 hours before administering caffeine and second 2 hours after administering caffeine | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in renal and Splanchnic oxygenation index pre and post caffeine administration Change in Cerebral, mesenteric, celiac artery doppler pre and post caffeine administration Seizure burden before and after caffeine Heart Rate Variability index before and after caffeine NPASS (Pain score) before and after caffeine Timepoint: Before and after caffeine administration between 36 to 50 hours of age | — |
Countries
India
Contacts
Public ContactReema Garegrat
Perinatal Brain Research Centre and Gupta Neonatal Hospital
Outcome results
None listed