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An act of comparing of three anesthetic drugs that is Dexmedetomidine- Ketamine- Propofol together compared with two drug group which is Ketamine-Propofol together for recovery quality

Comparison of Dexmedetomidine-Ketamine-Propofol combination versus Ketamine-Propofol combination for recovery characteristics in gynecological procedure: A randomized controlled study - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065195
Enrollment
64
Registered
2024-04-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group DKP: Inj. Dexmedetomidine + Inj. Ketamine-Propofol: 1 microgram/kg dexmedetomidine diluted to 20 ml and will be given intravenously as bolus over period of 10 minute before admini

Sponsors

Baroda Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.patients posted for gynaecological procedure having procedure time less than 30 minutes 2.ASA I, II, III 3.age/ sex 18-65 years, female 4.BMI less than 30kg/ m2 5.patient belonging to mallamppati grading I- II on airway assessment

Exclusion criteria

Exclusion criteria: 1. Inability or refusal to follow the study protocol 2. Patient with uncontrolled medical conditions like hypertension, diabetes mellitus, renal failure, active seizure, raised intracranial pressure etc. 3. Patient with sever cardiovascular or pulmonary pathology, sever renal or liver disorders. 4. Patient having neuro psychiatric disorders, H/o drug or alcohol abuse etc.

Design outcomes

Primary

MeasureTime frame
To compare post procedure recovery characteristics for: a)Recovery time (Time to achieve University of Michigan sedation scale 1 (UMSS 1)) b)Post procedure Emergence agitation: yes/no c)Over all patient satisfaction scoreTimepoint: At end of procedure

Secondary

MeasureTime frame
1.To monitor stability by monitoring systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse rate, peripheral oxygen saturation during procedure & maintain them within 20% of baseline value 2.To record total requirement of incremental dose of ketamine-propofol during procedure 3.Peri-procedure adverse events 4.Post procedure discharge time will be observedTimepoint: From baseline till end of procedure

Countries

India

Contacts

Public ContactDr Neha shah

Baroda Medical College

nehakinitshah@gmail.com9898019910

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026