To compare effect of two drugs as addition to a local anaesthetic drug in landmark guided plane block for post operative pain relief in abdominal surgeries

Evaluation of analgesic efficacy of clonidine vs dexmedetomidine as adjuvant to bupivacaine in landmark guided erector spinae plane block for post operative pain relief in patients undergoing abdominal surgeries - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065176

Enrollment

Registered

2024-04-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison between two alpha 2 agonist drugs: Evaluation of analgesic efficacy of clonidine 1 micrograms per kilogram vs dexmedetomidine 0.5 micrograms per kilogram as adjuvant to 0.25%

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA Grade 1 and 2 2. Age between 18-60 years 3. Elective abdominal surgeries 4. Patients acceptance

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Age less than 18 and more than 60 3. ASA Grade 3 and 4 4. Patients posted for emergency surgeries 5. Patients with local infections at puncturing site 6. Patients with ischemic and rheumatic heart diseases 7. Patients with coagulation defects and patients on anti coagulants 8. Patients with neuromuscular disorders 9. Patients allergic to local anaesthetic drugs 10. Patient with known case of epilepsy, pregnancy, spine deformity and those who are not unable to understand the visual analogue score

Design outcomes

Primary

Measure	Time frame
To determine the post operative analgesia after the erector spinae plane block in patients undergoing abdominal surgeriesTimepoint: 24 hours	—

Secondary

Measure	Time frame
To evaluate the total dose of rescue analgesia and side effects in post operative periodTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactDr Singaravelan M

Vinayaka Missions Kirupananda Variyar Medical College and Hospital

premvijay55@gmail.com9003503592

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026