Comparing Safety and Effectiveness of Pill vs. Vaginal Medication for Labor Induction at Full Term

TO COMPARE SAFETY AND EFFICACY OF ORAL VS VAGINAL MISOPROSTOL FOR INDUCTION OF LABOUR AT TERM

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2024/04/065173

Enrollment

100

Registered

2024-04-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O610- Failed medical induction of labor

Interventions

Intervention1: Misoprostol tablet: Tablet misoprostol 25 micrograms given per vaginally Control Intervention1: Misoprostol Tablet: Tab 25 micrograms per oral given

Eligibility

Inclusion criteria

Inclusion criteria: Live singleton pregnancy of gestational age of 37–42 weeks. Multiparous women. A cephalic presentation. Post dated pregnancy. Premature rupture of membranes. Bishop score Reactive Non Stress test Clinically adequate pelvis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mode of delivery Induction-to-delivery interval in vaginal delivery Vaginal delivery within 24 hours. Timepoint: 24 HOURS	—

Secondary

Measure	Time frame
Number of doses of misoprostol needed to effect vaginal delivery Augmentation with oxytocin Incidence of failed induction Maternal adverse effects (nausea/vomiting, diarrhea, fever, postpartum hemorrhage, uterine rupture) Neonatal outcomes. Timepoint: 24 HOURS	—

Countries

India

Contacts

Public ContactNAINITA PATEL

JAWAHAR LAL NEHRU MEDICAL COLLEGE

dr.kamleshchaudhari@gmail.com9320568673

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026