Health Condition 1: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
BLDE deemed to be university
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either gender between 30-70years, diagnosed with Type 2 diabetic on treatment, not on any lipid lowering drugs and with Body mass index (BMI) less than 30
Exclusion criteria
Exclusion criteria: Patients age more than 70 years of either sex, pregnant and lactating women or diagnosed with severe renal or ischemic heart disease or with Proliferative retinopathy, thyroid disease and malignant tumours and Chronic alcoholics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sirtuin has emerged as an exciting target of several diseases such as neurodegenerative diseases, aging, diabetes, cancer, metabolic disorder, and heart disease. SIRT1 and SIRT6 can be regarded as an attractive target in the metabolic activity of glucose in light of animal studies conducted to develop new and effective antidiabetics. Hence the present study is focused on to study the correlation of Sirtuin 1 & 6 in type 2 DM patients on various antidiabetic therapy.Timepoint: It is a cross sectional observational study. Time point is end of the study after analysis of samples as we are checking for the sirtuin levels only once | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate Sirtuin 1 & Sirtuin 6 levels in patients on different antidiabetic & oral hypoglycaemic therapy. ALso to compare the HOMA index.Timepoint: It is a cross sectional observational study. Time point is end of the study after analysis of samples as we are checking for the sirtuin levels TSH levels Lipid profile fasting insulin FBS HbA1c only once | — |
Countries
India
Contacts
Public ContactDr Latha S
Shri B M Patil Medical College Hospital and Research Center
Outcome results
None listed