A prospective study to assess the effectiveness of hyaluronic acid in myringoplasty surgery

EVALUATING THE EFFICACY OF HYALURONIC ACID IN MYRINGOPLASTY- A PROSPECTIVE CONTROLLED CLINICAL TRIAL - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065134

Enrollment

Registered

2024-04-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H720- Central perforation of tympanic membrane

Interventions

Intervention1: Evaluating the efficacy of using Hyaluronic Acid in Myringoplasty surgery: 1 ml of Hyaluronic acid available as Sodium Hyaluronate 20mg/2ml is applied one time topically along with abso

Eligibility

Inclusion criteria

Inclusion criteria: 1. Dry ears, with out any ear discharge for atleast 6 weeks 2. No Tympanic membrane retraction pocket and cholesteatoma 3. AB (air-bone) gap less than 35 decibels 4. Normal ear ossicular function 5. Normal eustachian tube function 6. No immunodeficient conditions

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Better acceptance of graft in Myringoplasty and improvement of hearingTimepoint: 2nd week, 3rd week, 2nd month and 3rd month post operatively	—

Secondary

Measure	Time frame
Faster graft healing time in Myringoplasty.Timepoint: 10th, 15th & 20th post operative days	—

Countries

India

Contacts

Public ContactDr Ajmal A

VINAYAKA MISSIONS MEDICAL COLLEGE HOSPITAL, KARAIKAL

vemsrigeenan2@gmail.com09842774997

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026