Effectiveness of intravenous steroid vs perineural steroids as an additive in abdominal plane blocks in patient undergoing cesarian section - A Clinical trail

Efficacy of intravenous versus perineal dexamethasone as an adjuvant in transverse abdominis plane block for post operative analgesia following elective cesarean section - A randomised double blinded clinical trial - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065125

Enrollment

Registered

2024-04-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O759- Complication of labor and delivery, unspecified

Interventions

Intervention1: Intravenous dexamethasone: Inj.Dexamethasone of 8mg (2ml) will be given along with bilateral TAP block via interavenous route, the drug will be administered only once Control Interventi

Eligibility

Inclusion criteria

Inclusion criteria: 1.All pregnant women 2.ASA II patients

Exclusion criteria

Exclusion criteria: 1.Allergy to local anaesthetic drugs 2.Seizure disorders 3.Any intraoperative surgical complications 4.Prolonged duration of labour 5.If caesarean section is done under general anaesthesia 6.Dexamethasone Used During Intra Operative period 7.Patients having gestational diabetes mellitus

Design outcomes

Primary

Measure	Time frame
To assess and compare the duration of analgesia.Timepoint: At baseline, 2 hours, 4 hours, 6 hours, 8 hours, 10 hours, 12 hours, 16 hours, 20 hours and 24 hours	—

Secondary

Measure	Time frame
To assess & compare the loss of sensation to cold & touch in the abdominal wall dermatomes from T9 to L1, in the midline & midclavicular lines on both sides.Timepoint: Baseline, 2, 4, 6, 8, 10, 12, 16, 20, 24 hours;To assess & compare the static & dynamic post-op pain scores at 0, 2, 4, 6, 8, 10, 12, 16, 20, 24 hours using visual analog scale. Timepoint: Baseline, 2, 4, 6, 8, 10, 12, 16, 20, 24 hours;To assess & compare the time to first analgesic requirement.Timepoint: 8 hours & 12 hours;To measure the 24-hour cumulative rescue analgesic consumption.Timepoint: 24 hours	—

Measure

Time frame

To assess & compare the loss of sensation to cold & touch in the abdominal wall dermatomes from T9 to L1, in the midline & midclavicular lines on both sides.Timepoint: Baseline, 2, 4, 6, 8, 10, 12, 16, 20, 24 hours;To assess & compare the static & dynamic post-op pain scores at 0, 2, 4, 6, 8, 10, 12, 16, 20, 24 hours using visual analog scale. Timepoint: Baseline, 2, 4, 6, 8, 10, 12, 16, 20, 24 hours;To assess & compare the time to first analgesic requirement.Timepoint: 8 hours & 12 hours;To measure the 24-hour cumulative rescue analgesic consumption.Timepoint: 24 hours

—

Countries

India

Contacts

Public ContactNithin K

Sri Balaji vidyapeeth

drgayatrimishra@gmail.com8489332550

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026