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Comparison of the anesthetic efficacy of lidocaine 2% with articaine 4% in dental pain anesthesia.

Comparative Evaluation of Anesthetic Efficacy of two different Local Anesthetic Agents in Maxillary Posterior Teeth with Irreversible Pulpitis: A Prospective Randomized Double-Blind Study - Nil

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065122
Enrollment
104
Registered
2024-04-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: 2% lidocaine with 1:100,000: (1) 26 patients shall receive PSA nerve block injections using 1.8 ml of 2% lidocaine with 1:100,000 epinephrine, 15 minutes before the start of the root ca
‘‘faint, weak, or mild’’ pain corresponded to 0 to 3 cm
‘‘moderate’’ pain corresponded to 4 to 6 cm
and ‘‘strong, intense, and maximum possible’’ pain corresponded to above 7cm. On a random basis, 1)26 patients shall receive PSA nerve block injections using 2% lidocaine with 1:100,000 epinephrine, 2

Sponsors

EDE Sumit Nagaraj
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Those Patients who are at least 18 years old, having good oral and general health, possessing vital symptomatic maxillary posterior teeth,moderate to severe pain in the maxillary molar, a prolonged response to cold testing with an endofrost spray and an exaggerated response to electric pulp testing,the absence of any periapical radiolucency on radiographs except for a widened periodontal ligament, a vital coronal pulp on access opening, and the ability of subject to understand the use of pain scales.

Exclusion criteria

Exclusion criteria: Subjects younger than 18 years of age or older than 50 years of age, patients having active pain in more than 1 maxillary molar, subjects taking any pain-relieving medication including over-the-counter analgesics at least 12 hours before enrolment in the study and swelling near the tooth in question.

Design outcomes

Primary

MeasureTime frame
Subjective and Objective Signs of onset of complete pulpal anesthesia after the injection of the anesthetic agentTimepoint: 15 minutes after the injection of the anesthetic agent, and the same shall be verified by negative response to electric pulp testing

Secondary

MeasureTime frame
patients who have received the injection of the anesthetic agent must feel no pain during endodontic access opening & instrumentationTimepoint: complete pulpal anesthesia 15 minutes after the injection & no sensation of pain up to 1 hour.

Countries

India

Contacts

Public ContactDr Syed Mukhtar ArUnNisar Andrabi

Dr Ziauddin Ahmad Dental College & Hospital Aligarh Muslim University Aligarh

ashokoperative@yahoo.in9412732327

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026