Investigating the effectiveness of two different drugs in managing intraoperative shivering among patients undergoing surgery under spinal anesthesia

A comparative study to determine the efficacy of dexmedetomidine and nalbuphine for the treatment intraoperative shivering in the patients posted for surgery Under spinal anaesthesia - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/065027

Enrollment

Registered

2024-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: spinal anaesthesia: comparison of nalbuphine 0.08 mg/kg and dexmedetomidine 0.3ug/kg diluted in normal saline upto 10 ml given as slow intravenous bolus for treatment of intraoperative

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2

Exclusion criteria

Exclusion criteria: a) Allergic to any of the drugs b) Contraindication to spinal anaesthesia c) Obese patients BMI more than 30 d) ASA grade 3 and 4 e) Patients with coagulopathy, heart blocks and bradycardia, f) Pregnant and nursing mothers

Design outcomes

Primary

Measure	Time frame
To determine the efficacy of dexmedetomidine and nalbuphine in the treatment of intraoperative shivering in the patients scheduled for surgery under spinal anaesthesiaTimepoint: Start from the initiation of anaesthesia till the end of surgery at every 5 min in first half hour and every 15 min till the end of surgery	—

Secondary

Measure	Time frame
1) Time for cessation of shivering in (min) following drug administration 2) Grade of shivering following drug administration. 3) Time for reoccurrence of shivering (min) 4) Time for disappearance of shivering in case of recurrence 5) Side effects Timepoint: Start from the initiation of anaesthesia till the end of surgery at every 5 min in first half hour & every 15 min till the end of surgery	—

Countries

India

Contacts

Public ContactDr Urvashi

Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar

sachreetdr@gmail.com7888922797

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026