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Medicine to use to prevent pain in the throat after general anaesthesia.

Comparison of efficacy of pre-operative nebulized magnesium sulphate versus lidocaine on the prevention of post-intubation sore throat: a randomised control study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065024
Enrollment
80
Registered
2024-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Magnesium sulphate 250 mg: Patients nebulised with magnesium sulphate 2.5 ml plus sterile water 2.5 ml before induction of general anaesthesia Control Intervention1: Lignocaine 2% 100 m

Sponsors

DR E R Revaanth
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patient willing to give informed written consent 2 Adult normotensive patients aged between 18 to 60 years posted for surgery 3 American society of Anaesthesiology (ASA) grade 1 or 2

Exclusion criteria

Exclusion criteria: 1 Patients scheduled for surgeries under General anaesthesia more than 4hrs duration 2 Patients with neuromuscular disease, cardio vascular, respiratory, renal and hepatic derangement 3 Patients has allergy or hypersensitivity to drugs 4 Attempt of nasogastric tube pre-operatively and intra-operatively 5 Patients undergoing head and neck surgery, laparoscopic surgery, prone positing during surgery. 6. Patient with incidence of post laryngospasm. 7 Patient with anticipated or attempted difficult intubation. 8 Patient intubated with any maneuver other than laryngoscope eg; i-gel, laryngeal mask airway or fiber-optic guided. 9 Patient with history of pre-operative sore throat, using steroid, or analgesic in last 48h 10 Pregnant women, psychiatric illness.

Design outcomes

Primary

MeasureTime frame
To compare the Post-operative Sore throat after Extubation at rest and on swallowingTimepoint: IMMEDIATE POSTOP 4 hours , 8 hours, 12 hours, 24 hours and 48 hours

Secondary

MeasureTime frame
To look for other side effects like nausea vomiting sedation cough laryngospasam hoarseness of voice dysphagia dysphonia To assess hemodynamic changes in response to laryngoscopy and intubation Timepoint: IMMEDIATE POSTOP 4 hours , 8 hours, 12 hours, 24 hours and 48 hours

Countries

India

Contacts

Public ContactDR. Ramachandraiah R

Bangalore Medical College and Research Institute.

swathisaggi@gmail.com9972454989

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026