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A Randomised Comparision of amisulpride with dexamethasone and ondansetron with dexamethasone in preventing postoperative nausea and vomiting in adult patients undergoing laparoscopic cholecystectomy

Comparison of amisulpride with dexamethasone and ondansetron with dexamethasone for prevention of postoperative nausea and vomiting in adult patients undergoing laparoscopic cholecystectomy: A Randomised Comparative study - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/065000
Enrollment
208
Registered
2024-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: AMISULSPRIDE WITH DEXAMETHASONE AND ONDANSETRON WITH DEXAMETHASONE: Just after the induction of anaesthesia Group A patients will be given a single dose of Amisulpride 5mg IV+ Dexameth

Sponsors

ABVIMS and Dr RML Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing Laparoscopic Cholecystectomy

Exclusion criteria

Exclusion criteria: Surgery lasting longer than 4 hours. Patients receiving chemotherapy or radiotherapy within the past four weeks. Use of any drugs with emetic or antiemetic action within 24 hours prior to surgery. Pregnant females. Patients with liver /kidney diseases.

Design outcomes

Primary

MeasureTime frame
To compare amisulpride with dexamethasone and ondansetron with dexamethasone in the prevention of postoperative nausea and vomiting and in adult patients undergoing laparoscopic cholecystectomy using PONV scoreTimepoint: From the end of surgery to next 24 hours

Secondary

MeasureTime frame
1. Timing and total requirement of rescue antiemetic. 2. Satisfaction of patient 3. Occurrence of adverse effects, like headache, dizziness, drowsiness, pain at the site of injection etc. Timepoint: From the end of surgery to next 24 hours

Countries

India

Contacts

Public ContactNisha Kachru

Atal Bhiari Vajpayee Institute of Medical Sciences and Dr Ram Manohar Lohia Hospital

nishakachru@yahoo.co.uk9810488435

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026