Better drug among Carbetocin, Oxytocin and Tranexemic acid to control minor Post Partum Hemorrhage- A DOUBLE BLINDED, THREE-ARMED RANDOMIZED CONTROL TRIAL

MANAGEMENT OF MINOR ATONIC POST PARTUM HEMORRHAGE AFTER AMTSL- WITH CARBETOCIN, TRANEXEMIC ACID AND OXYTOCIN CONTROLS- A DOUBLE BLINDED, THREE-ARMED RANDOMIZED CONTROL TRIAL - OxyTraCarb

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/064978

Enrollment

450

Registered

2024-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O720- Third-stage hemorrhage

Interventions

Intervention1: drug- carbetocin, tranexamic acid.: Inj.Oxytocin 20units total , 10units i v and 10 units i.m Inj Tranexemic Acid 1 gram i.v stat Within 5 minutes of placental delivery Inj Carbetoc

Eligibility

Inclusion criteria

Inclusion criteria: •Term pregnancies getting admitted to KIMS labour room,who deliver vaginally and have minor PPH (500- 1000ml).

Exclusion criteria

Exclusion criteria: CNS diseases like epilepsy, Liver diseases, Hypertension cases, patients with bleeding disorders, Placenta previa cases

Design outcomes

Primary

Measure	Time frame
1.Time taken by each drug to achieve well contracted state of uterus 2.Total amount of blood loss at the end of 5 minutes after fetal delivery Timepoint: 5 minutes	—

Secondary

Measure	Time frame
Total amount of blood loss. Time taken to reach a “well contracted ? state of uterus. Need for additional non-surgical or surgical methods further. Timepoint: next 30 mins after the delivery of the placenta	—

Countries

India

Contacts

Public ContactAnnie Jesline Dmello

Karnataka Institute of Medical Sciences and Research Hospital, Hubli

a96jesline@gmail.com08310508268

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026