Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Atracurium: Intravenous injection of 0.5mg/kg loading bolus dose and maintenance 0.1mg/kg every 15-30 min interval for a total duration of 3 hours
.
Control Intervention1: Cisatracuri
Sponsors
Bhaskar Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Patients belonging to American Society of Anesthesiologists Grade I & II. Surgeries requiring General Anesthesia with endotracheal intubation. Surgeries of an anticipated duration of at least 90 min.
Exclusion criteria
Exclusion criteria: Anticipated difficult intubation with Mallampati grade 3 or 4. Any known case of neuromuscular disease. Patient on any medication known to interact with Neuromuscular blocking drugs. Patient with known allergies to any drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset Time, Duration Time and Recovery Time of muscle relaxation with the help of Train-of-four (TOF) score using acceleromyograph monitor.Timepoint: Baseline Induction of Anaesthesia Intubation Maintenence every 30 Minutes untill the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the hemodynamics during intraoperative period. To monitor adverse reactions if any Signs of Histamine release like Bronchospasm Urticaria Timepoint: Every 5 minutes until the end of surgery Adverse reactions for 24 hours | — |
Countries
India
Contacts
Public ContactKarkala Srikanth Reddy
Bhaskar Medical College
Outcome results
None listed