Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Application of transdermal fentanyl (25 µg/hr) and buprenorphine (10 µg/hr) patches: We will apply one-time single fentanyl patch whose dose or rate of delivery will be 25 µg/hr or bupr
Sponsors
Himalayan Institute of Medical Sciences, Swami Rama Himalayan University
Eligibility
Inclusion criteria
Inclusion criteria: Age 18 to 60 years. Female patients. Patients undergoing radical abdominal hysterectomy. Written informed consent by patients. Grades 1 and 2 of the American Society of Anesthesia physical status.
Exclusion criteria
Exclusion criteria: 1.Pregnant females. 2.Patients with history of pre-existing lung and cardiac disease. 3.Patients with impaired kidney or liver function. 4.Patients who have experienced an upper respiratory illness in the prior four weeks. 5.Patients with history of smoking, respiratory or gastrointestinal infection. 6.Patients with history of any allergy to any study drug. 7.Patients on antiepileptics or antidepressants, NSAIDS, or any type of pain medicine for longer than three months. 8.Patients with any syndrome of chronic pain. 9.Inability to understand pain assessment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the effectiveness of fentanyl patch and buprenorphine patch in controlling immediate postoperative pain using Numerical rating scaleTimepoint: 72 hours from recovery of anesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic fluctuation and the side effects of fentanyl and buprenorphine patches by using Bellville grading scale for nausea and vomiting, and Ramsay sedation score for sedationTimepoint: 72 hours from recovery of anesthesia | — |
Countries
India
Contacts
Public ContactAbhimanyu Singh Pokhriyal
Himalayan Institute of Medical Sciences, Swami Rama Himalayan University
Outcome results
None listed