Comparative study in which participants will receive NSAIDs eye drops at different intervals after cataract surgery and the visual outcome and post operative complications will be compared.

To compare visual outcome, post-operative inflammation and Cystoid macular edema in Early v/s late initiation of NSAIDs - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/04/064956

Enrollment

220

Registered

2024-04-01

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H598- Other intraoperative and postprocedural complications and disorders of eye and adnexa, not elsewhere classified

Interventions

Intervention1: Nepafenac: Topical Nepafenac 0.1% thrice daily for 1 month starting at post operative day 21. Control Intervention1: Nepafenac: Topical Nepafenac 0.1% thrice daily for 1 month from post

Eligibility

Inclusion criteria

Inclusion criteria: Visually significant cataract Uneventful phacoemulsification with IOL implantation

Exclusion criteria

Exclusion criteria: 1)Diabetic retinopathy and other retinal pathologies 2)History of uveitis. 3)Mature, hyper mature, traumatic, complicated cataract. 4) Known or suspected hypersensitivity to Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) 5) Cystoid macular edema in the fellow eye. 6) Vascular occlusive disorders. 7) Associated Macular pathologies 8)Pregnant and lactating women 9) Patients with mental illness 10)Non visualization of fundus 11) H/O steroid responsiveness 12) H/O Prostaglandin analog usage 13) Dry eye

Design outcomes

Primary

Measure	Time frame
Improvement in visual acuityTimepoint: 1 year	—

Secondary

Measure	Time frame
1)Reduced incidence of post operative inflammation. 2)Reduced incidence of CME on late initiation of prophylactic NSAID therapy. Timepoint: 1 year	—

Countries

India

Contacts

Public ContactDr. Haripriya Aravind

Aravind Eye Hospital, Chennai

haripriya@aravind.org9442643561

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026