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Comparison study between perioperative lidocaine and dexmedetomidine infusion for postoperative pain in laparoscopic cholecystectomy patients

Comparison of effect of perioperative infusion of lidocaine vs dexmedetomidine on post operative pain in patients undergoing laparoscopic cholecystectomy - NIL

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/04/064953
Enrollment
66
Registered
2024-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: LIDOCAINE: IV INFUSION LOADING DOSE OF 1.5MG/KG AND MAINTAINENCE DOSE OF 2MG/KG/HR TILL END OF SURGERY Control Intervention1: DEXMEDETOMIDINE: IV INFUSION LOADING DOSE OF 1MCG/KG AND MA

Sponsors

Eras Lucknow Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing Laparoscopic Cholecystectomy under General Anesthesia. Age between 18 – 60 years ASA Grade I and II

Exclusion criteria

Exclusion criteria: BMI >30kg/m2. Pregnant and Lactating mothers Patients having sinus bradycardia or heart blocks, Patients On steroids. History of Allergy to study drugs

Design outcomes

Primary

MeasureTime frame
The Efficacy of Intravenous Lidocaine or Intravenous Dexmedetomidine for post operative pain relief following laparoscopic cystectomy would be determined by this studyTimepoint: Surgery of max 1hr15mins and followed up for 12hours postoperative period.

Secondary

MeasureTime frame
The Efficacy of Intravenous Lidocaine or Intravenous Dexmedetomidine for Recovery profile & time to first rescue analgesic following laparoscopic cystectomy would be determined by this studyTimepoint: Surgery of max 1hr15mins & followed up for 12hours postoperative period

Countries

India

Contacts

Public ContactAnam Rizwan

Eras Lucknow Medical College and Hospital

shirin_grmc@yahoo.com7388732089

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026