Health Condition 1: G409- Epilepsy, unspecified Health Condition 2: M818- Other osteoporosis without currentpathological fracture
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Nitte Universisty Grant
Eligibility
Inclusion criteria
Inclusion criteria: All patients on Antiepileptic drugs for a minimum period of 6months Females Age more than or equal to 20years and premenopausal Males Age more than or equal to 20years and below 65years of age Patients with comorbidities that may not have a major impact on bone health like Hypothyroidism with euthyroid status Hypertension Dyslipidemia Well controlled Diabetes mellitus
Exclusion criteria
Exclusion criteria: Presence of chronic comorbidities which could affect bone mineral density like Chronic kidney disease Primary hyperparathyroidism Rheumatoid arthritis Uncontrolled Diabetes (HbA1C above 7) Hyperthyroidism Intake of drugs like steroids, estrogen, recombinant Parathormone Calcitonin Diuretics Anticoagulants Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the alterations in bone mineral density, trabecular bone score and bone turnover markers induced by antiepileptic drugs in IndiansTimepoint: Baseline only, since the study is of cross sectional design | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the effect of antiepileptic drugs on 25hydroxy vitamin D levels To compare TBS FRAX with FRAX tool to predict fracture risk Timepoint: Baseline only, since the study is of cross sectional design | — |
Countries
India
Contacts
Public ContactDr AKHILA BHANDARKAR P
Justice K.S Hegde Medical Academy
Outcome results
None listed