Effect of two orally given medicines on anesthesia of lower back tooth with infection

Effectiveness of oral premedication on anesthetic success of Inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis using Dexamethasone and combination of Dexamethasone and Ibuprofen A double blinded randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064923

Enrollment

Registered

2024-03-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K040- Pulpitis

Interventions

Intervention1: Effectiveness of oral premedication on anesthetic success of inferior alveolar nerve block in mandibular molars with symptomatic irreversible pulpitis using dexamethasone: To evaluate t

Eligibility

Inclusion criteria

Inclusion criteria: Healthy adult patients aged 18 to 45 years Presence of irreversible pulpitis with moderate to severe pain in mandibular molars, without any signs of periapical involvement. Patients not taken analgesics for at least 12 hours before enrollment in the study

Exclusion criteria

Exclusion criteria: Patients with allergies and hypersensitivity to medications, local anesthetic solution, or its components Pregnant or nursing women Immunocompromised patients Patients with active sites of pathosis in the area of injection

Design outcomes

Primary

Measure	Time frame
PainTimepoint: Before premedication 15 minutes after LA During File insertion	—

Secondary

Measure	Time frame
PainTimepoint: During Access opening During File insertion	—

Countries

India

Contacts

Public ContactPoojamol P V

Government Dental College Kottayam

drshobak@gmail.com9745205407

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026