Health Condition 1: J00-J99- Diseases of the respiratory system
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients in the age group 18 to 75 years 2. Patients presenting with hypercapnic respiratory failure with pco2 more than 45 mm of HG and PH less than 7.35
Exclusion criteria
Exclusion criteria: 1. hemodynamic instability 2. Claustrophobic patients 3. Pregnant patients 4. Patients diagnosed with pneumothorax, hemoptysis, hematemesis 5. Patients with significant comorbidities affecting the outcome 6. Patient with ABG showing pH less than 7.20 7. Patients with GCS less than 7
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome will be measured by monitoring the rate of change of PH, PaCO2, PaO2, Respiratory rate, Heart Rate, Blood pressure, GCSTimepoint: Primary outcome will be assessed at the start of study followed by at the end of 6 hours, 24 hours , 48 hours and at the time of discharge after initiating the study | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes assessed by evaluating number of days on NIV , no of hospital days, no of intubation and mortality rate. Timepoint: secondary out come will be assessed at the end of study | — |
Countries
India
Contacts
Srm Medical college hospital and Research institute