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Comparison study between two modes of non invasive ventilation, ivaps and ST modes in patients presented with hypercapnic respiratory failure

Comparison study of intelligent volume assured pressure support and spontaneous timed mode in hypercapnic respiratory failure. A randomized clinical trial - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064917
Enrollment
60
Registered
2024-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: intelligent volume-assured pressure support (IVAPS): To compare efficacy intelligent volume-assured pressure support (IVAPS) and S/T conventional mode in patients with Hypercapnic fai

Sponsors

SRM Medical college hospital and Research institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients in the age group 18 to 75 years 2. Patients presenting with hypercapnic respiratory failure with pco2 more than 45 mm of HG and PH less than 7.35

Exclusion criteria

Exclusion criteria: 1. hemodynamic instability 2. Claustrophobic patients 3. Pregnant patients 4. Patients diagnosed with pneumothorax, hemoptysis, hematemesis 5. Patients with significant comorbidities affecting the outcome 6. Patient with ABG showing pH less than 7.20 7. Patients with GCS less than 7

Design outcomes

Primary

MeasureTime frame
Primary outcome will be measured by monitoring the rate of change of PH, PaCO2, PaO2, Respiratory rate, Heart Rate, Blood pressure, GCSTimepoint: Primary outcome will be assessed at the start of study followed by at the end of 6 hours, 24 hours , 48 hours and at the time of discharge after initiating the study

Secondary

MeasureTime frame
The secondary outcomes assessed by evaluating number of days on NIV , no of hospital days, no of intubation and mortality rate. Timepoint: secondary out come will be assessed at the end of study

Countries

India

Contacts

Public ContactDr S Subramanian

Srm Medical college hospital and Research institute

drssmani@gmail.com8667629090

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026