Vitamin D versus placebo (glucose sachets) on reducing cancer related fatigue and pain in patients of head and neck cancer

Vitamin D versus placebo on reducing cancer related fatigue and pain in patients of head and neck cancer - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064906

Enrollment

Registered

2024-03-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 2: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: Vitamin D: Vitamin D is a fat-soluble vitamin and is a steroid hormone. It plays an important role in maintaining bone health and calcium homeostasis and immune function. Vitamin D help

Eligibility

Inclusion criteria

Inclusion criteria: 1. All cases of previous head and neck squamous cell cancer, in one of the following subsites of head and neck area: oral cavity, oropharynx, larynx, hypopharynx, nasopharynx, paranasal sinus, salivary gland, or having suffered of a cancer of unknown primary (CUP) in head and neck area. 2. Adults more than 18 years of age. 3. Patients who are on radiation therapy, with curative or postoperative intent. 4. Patients with vitamin D level 5. Patients giving informed written consent.

Exclusion criteria

Exclusion criteria: 1. Patients not diagnosed with cancer 2. Patients having cancer of area other than head and neck 3. Head and neck cancer other than squamous cell carcinoma (adenocarcinoma, mucoepidermoid carcinoma, rhabdomyosarcoma, angiofibroma, basal cell carcinoma) 4. Patients with psychiatric disorder 5. Patients not giving consent for the intervention. 6. Patients diagnosed with diabetes, neuropathies, hypertension, renal disease, heart disease, hypothyroidism, autoimmune disease, blood dyscariasis. 7. Vitamin D > 30 ng/ml

Design outcomes

Primary

Measure	Time frame
The primary aim of the study is to compare the effect on cancer related fatigue in patients receiving vitamin D supplementation as compared to those who are not.Timepoint: 2 months and 3 months	—

Secondary

Measure	Time frame
The secondary aim of the study is to study the effect of vitamin D supplementation on pain in head and neck cancer patients.Timepoint: 2 months and 3 months	—

Countries

India

Contacts

Public ContactRajesh Mahajan

SMGS, Government Medical College and Hospital, Jammu, Jammu and Kashmir

drpkalsotra@yahoo.co.in9419141505

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026