Health Condition 1: P073- Preterm [premature] newborn [other]
Conditions
Interventions
Intervention1: Injection Vitamin K1: Single dose prophylaxis Intravenous 1 mg in babies weighing more than or equal to 1 kg
Intravenous 0.5 mg in babies weighing less than 1 kg
Control Intervention1:
Sponsors
Divya A
Eligibility
Inclusion criteria
Inclusion criteria: Preterm infants between 28 0/7 weeks to 33 6/7 weeks
Exclusion criteria
Exclusion criteria: Fetal intracranial Hemorrhage History of Alloimmune Thrombocytopenia Maternal antiplatelet antibodies Major Congenital abnormalities such as congential diaphragmatic hernia, anorectal malformation, VACTERL association, intestinal atresia Bruised at Birth Large Subgaleal bleed Mother on treatment with vitamin k antagonist, Heparin, warfarin APGAR BELOW 3 at 1 minute of life
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Protein induced by vitamin K absence-II levels in bloodTimepoint: Day 5 and Day 30 | — |
Secondary
| Measure | Time frame |
|---|---|
| Any bleeding manifestationsTimepoint: till 6 months of life;Bronchopulmonary dysplasiaTimepoint: till hospital stay;Intraventricular hemorrhageTimepoint: till 44 weeks post menstrual age;late onset sepsisTimepoint: till hospital stay;Nectrotising enterocolitisTimepoint: till hospital stay;Retinopathy of prematurityTimepoint: till 44 weeks post menstrual age | — |
Countries
India
Contacts
Public ContactSubash S
SRM Medical College Hospital and Research Centre
Outcome results
None listed