To compare the effectiveness of 3 drugs: Bupivacaine, Ropivacaine mixed with Dexmedetomidine, and Ropivacaine during planned surgery done under spinal anaesthesia.

Comparative Study of 0.75% Hyperbaric Ropivacaine,0.75% Hyperbaric Ropivacaine with dexmedetomidine and 0.5% Hyperbaric Bupivacaine In Spinal Anaesthesia For Elective Surgery - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064896

Enrollment

Registered

2024-03-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Sub-Arachnoid Block: Under all aseptic precautions, 3 ml of 0.5% Bupivacaine OR 0.75% Ropivacaine OR 0.75% Ropivacaine with 3 mcg dexmedetomidine will be given in L3-L4 intervertebral s

Eligibility

Inclusion criteria

Inclusion criteria: 1: ASA grades 1 and 2 2: Patients undergoing elective lower abdominal Surgeries, perineal Surgeries and lower limb surgeries

Exclusion criteria

Exclusion criteria: 1:Patient refusal 2:Pre-existing Peripheral Neuropathy 3:Sepsis/local skin infection at the site of local anaesthetic administration 4:Allergy to local anaesthetic 5:Bleeding diathesis and coagulation disorder 6:Major cardio-respiratory disorder

Design outcomes

Primary

Measure	Time frame
1 : Sensory block (min) 2 : Motor block (min) Timepoint: SENSORY BLOCK 1: Onset time to T10 - time taken for sensory blockade to pain at T10 level since the time of Drug injection by Pin Prick Method 2: Maximal sensory level 3: Time to maximal Sensory level 4: Time to two dermatome regression 5: Time to regression to T10 6: Time to regression to L1 MOTOR BLOCK 1 :Time to complete block as per Modified Bromage Scale 2 :Time to complete recovery	—

Measure

Time frame

1 : Sensory block (min) 2 : Motor block (min) Timepoint: SENSORY BLOCK 1: Onset time to T10 - time taken for sensory blockade to pain at T10 level since the time of Drug injection by Pin Prick Method 2: Maximal sensory level 3: Time to maximal Sensory level 4: Time to two dermatome regression 5: Time to regression to T10 6: Time to regression to L1 MOTOR BLOCK 1 :Time to complete block as per Modified Bromage Scale 2 :Time to complete recovery

—

Secondary

Measure	Time frame
1: Effect on hemodynamics 2: Incidence of adverse effects 3: Post-operative analgesic requirement Timepoint: 1: Within 24 hours post surgery	—

Countries

India

Contacts

Public ContactVIDYA SAGAR CHAUBEY

Bharat Ratna late Shri Atal Bihari Vajpayee Memorial Medical College,Rajnandgaon

kosamdurga@gmail.com9826075062

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026