To determine the effects of platelet lysate on orthodontic tooth movement - An Invivo Study

Effects of platelet lysate on the rate of orthodontic tooth movement - A Single-center, split mouth, Randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064889

Enrollment

Registered

2024-03-28

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: interventional side - platelet lysate: platelet lysate is saturated by growth factors, proteins, cytokines, and chemokines obtained from Mothercell Regenerative centre Pvt Ltd Interven

Duration: 1 month: Platelet lysate will be obtained from Mothercell Regenerative centre Pvt Ltd & it will be inject in the buccal, palatal & distal sides of canine during the retraction phase Control

Eligibility

Inclusion criteria

Inclusion criteria: Angle’s class I with bimaxillary protrusion & Angle’s class II div I Malocclusion (requires 1st premolar extraction) Minimum crowding ( less than 3mm) or minimum spacing ( less than 4mm) No previous history of orthodontic treatment No systemic diseases;

Exclusion criteria

Exclusion criteria: Patients reported regular use of medications that affect the orthodontic tooth movement such as NSAIDs, Steroids etc Teeth with severe displacements ( such as the ectopic eruption of canine)

Design outcomes

Primary

Measure	Time frame
shorten the duration of the orthodontic treatment period (during canine retraction)Timepoint: 3-4 months	—

Secondary

Measure	Time frame
able to find out better biomodulatorTimepoint: 3-4 months	—

Countries

India

Contacts

Public ContactDr Prabhakar Krishnan

VMRF -DU

drprabhakar84@gmail.com9843688271

Outcome results