Health Condition 1: - Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Amisulpride: Group A- will receive 5mg of Amisulpride
Control Intervention1: Dexamethasone: Group D- will receive 8mg of Dexamethasone
Sponsors
Dr Amit Pradhan
Eligibility
Inclusion criteria
Inclusion criteria: ASA 1& 2 Patients posted for elective Laparoscopic cholecystectomy under endotracheal general anaesthesia
Exclusion criteria
Exclusion criteria: 1.Any hypersensitivity to the study drugs 2.Administration of antiemetic/steroid 24 hrs prior to anaesthesia 3.Administration of Emetogenic anticancer chemotherapy in previous 4 weeks 4.Pregnant/lactating females 5.Patients on treatment with levodopa/ carbidopa 6.Cardiac arryhthmia, QT interval abnormality 7.Hypokalemia,hypomagnesemia 8.Pre-existing vestibular disease 9.Need of naso/oro-gastric tube after surgery 10.Requirement of post operative mechanical ventilation
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1 Incidence and severity of significant nausea 2 Incidence of retching or vomiting 3 Time to first requirement of rescue antiemetic 4 Number of times of requirement of rescue antiemetic 5 VAS Score for pain 6 Adverse effects like infusion site pain, constipation and flatulence Timepoint: 24 hours | — |
Primary
| Measure | Time frame |
|---|---|
| To compare the proportion of Complete Response(defined as no episodes of nausea, retching or vomiting) upto first 24 hours after surgeryTimepoint: 24hours | — |
Countries
India
Contacts
Public ContactDr K B Tharun Kumar
KIMS, Bhubaneswar
Outcome results
None listed