Comparison between continuous administration of two sedative drugs on their effect on vitals of patient undergoing laparoscopic removal of gall bladder

Comparison of dexmedetomidine and clonidine infusion on hemodynamic stability in patients undergoing laparoscopic cholecystectomy. A double blind randomised controlled trial - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064823

Enrollment

Registered

2024-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison between two alpha 2 drugs: Comparison of dexmedetomidine and clonidine infusion on hemodynamic stability in patients undergoing laparoscopic cholecystectomy done from 30 minu

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade 1 and 2 2. Age between 20 to 60 years 3. Patient giving valid informed consent

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Age more than 60 and less than 20 years 3. ASA grade 3 and 4 4. Patients with Ischaemic and Rheumatic heart disease 5. Patients with coagulation defects and patients on anticoagulants 6. Pregnant and lactating patients 7. Patients allergic to these drugs

Design outcomes

Primary

Measure	Time frame
To evaluate the controlled hemodynamic response between two infusions which are blood pressure mean arterial pressure heart rate end tidal CO2 and oxygen saturationTimepoint: 30 minutes prior induction of anaesthesia upto extubation	—

Secondary

Measure	Time frame
To compare the controlled hemodynamic stability between two infusions after extubation in recoveryTimepoint: 10 to 15 minutes post extubation	—

Countries

India

Contacts

Public ContactDr Peerla Abdul Rahaman

Vinayaka Missions Kirupananda Variyar Medical College and Hospital Chinnaseeragapadi Salem

premvijay55@gmail.com9003503592

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026