Blue Laser and Antibiotics in the treatment of Periodontitis

Comparative analysis of the antimicrobial effect of Low Level Light Therapy versus Systemic Antimicrobials as an adjunct in the non surgical treatment of Stage 3 & 4 Periodontitis A Procalcitonin guided randomised controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064817

Enrollment

Registered

2024-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Non surgical periodontal therapy: full mouth scaling and root planing in one session using a combination of ultrasonic scaler and hand scaling instruments Control Intervention1: Low Lev

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age: 45 -60yrs 2. Stage 3 & Stage 4 Periodontitis patients (According to AAP & EFP 2017 Classification) 3. Minimum of 20 teeth, excluding third molars to be present.

Exclusion criteria

Exclusion criteria: 1. Any systemic or debilitating disease affecting periodontal health. 2. Immunocompromised patients 3. Regular NSAIDS and Aspirin use 4. Regular anti-inflammatory medication use 5. Antimicrobial use in the last three months 6. Antimicrobial mouthwash use in the last three months 7. Surgical periodontal treatment in the last three months 8. Pregnant or lactating women 9. Former or current smokers 10. Former or current alcoholics 11. Active carious lesions

Design outcomes

Primary

Measure	Time frame
Serum Procalcitonin, Serum CRPTimepoint: Baseline, 4 weeks and 12 weeks	—

Secondary

Measure	Time frame
Plaque index, Gingival index,Probing pocket depth, CAL, RALTimepoint: baseline, 1 month, 3 months	—

Countries

India

Contacts

Public ContactBenedicta Theresa Abraham

Bangalore Institute of Dental Sciences and Hospital

docranga@yahoo.com9844292297

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026