Comparison of 2 drugs dexmedetomidine and propofol for sedation (inducing sleep) during orthopedic surgeries in patients undergoing upper limb block

Intravenous dexmedetomidine versus propofol for moderate intraoperative sedation during brachial plexus block in orthopedic surgeries - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2024/03/064796

Enrollment

Registered

2024-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: V220- Motorcycle driver injured in collision with two- or three-wheeled motor vehicle in nontraffic accident Health Condition 2: V124- Pedal cycle driver injured in collision with two- or three-wheeled motor vehicle in traffic accident

Interventions

Intervention1: Brachial plexus block: Interscalene, supraclavicular and axillary block will be given to achieve brachial plexus block Drug lignocaine adrenaline 10 ml Bupivacine 0.5% 20 ml Route infil

Eligibility

Inclusion criteria

Inclusion criteria: ASA I-II BMI 18.5-35 Patients undergoing elective orthopedic surgeries under brachial plexus block

Exclusion criteria

Exclusion criteria: Hemodynamic instable patients Allergy to any of study medication Known hypersensitivity to local anaesthetics Pregnancy Infection at the site of block Pre existing peripheral neuropathy Patient refusal

Design outcomes

Primary

Measure	Time frame
Level of sedation assessed by Ramsay Sedation Scale Alertness of the patient assessed by Modified Observers Assessment of Alertness/Sedation Timepoint: RSS at every 5 minutes till end of surgery MOAA/S at every 5 minutes till end of surgery	—

Secondary

Measure	Time frame
Mean arterial BP, HR, RR , arterial oxygen saturation Incidence of adverse effects Duration of sedation Type of peripheral nerve block Duration of surgery Intraoperative requirement of ephedrine VAS score for pain Patient satisfaction scoreTimepoint: BP at every 5 minutes till end of surgery HR at every 5 minutes till end of surgery RR at every 5 minutes till end of surgery Arterial oxygen saturation at every 5 minutes till end of surgery	—

Measure

Time frame

Mean arterial BP, HR, RR , arterial oxygen saturation Incidence of adverse effects Duration of sedation Type of peripheral nerve block Duration of surgery Intraoperative requirement of ephedrine VAS score for pain Patient satisfaction scoreTimepoint: BP at every 5 minutes till end of surgery HR at every 5 minutes till end of surgery RR at every 5 minutes till end of surgery Arterial oxygen saturation at every 5 minutes till end of surgery

—

Countries

India

Contacts

Public ContactDr Pooja Paul

BRLSABVM medical college

Kosamdurga@gmail.com9826075062

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026