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COMPARISON OF MEDICINES TO STUDY EFFECTS LIKE BLOOD PRESSURE, HEART RATE VARIATIONS AND SENSORY AND MOTOR CHARACTERISTICS IN SPINAL ANAESTHESIA

A COMPARATIVE STUDY OF INTRATHECAL DEXMEDETOMIDINE VERSUS CLONIDINE AS ADJUVANT TO 0.75% HYPERBARIC ROPIVACAINE IN INFRA UMBILICAL SURGERIES :A RANDOMISED CLINICAL TRIAL - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064794
Enrollment
70
Registered
2024-03-27
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M859- Disorder of bone density and structure, unspecified Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: 0.75% hyperbaric Ropivacaine 3ml + dexmedetomidine 5 mcg: After adequate preoperative evaluation, patient will be brought inside operation theatre.Blood pressure, ECG leads, pulse oxime

Sponsors

Dr Soumya Patted
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of age group 18-60 years undergoing infraumbilical surgeries under supbarchnoid block. 2. Patients willing to give written informed consent 3. Patients belonging to ASA I and II

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
1) To compare the block characteristics of intrathecal Dexmedetomidine versus Clonidine as an adjuvant to 0.75% Hyperbaric Ropivacaine in terms of the onset and duration of sensory block and motor block 2) To compare the duration of post operative analgesiaTimepoint: From time of intrathecal injection to every 30 seconds till the loss of sensation at T10 dermatomal level and thereafter at 2 mins intervals till the maximum level of sensory blockade is achieved and subsequently at 30 mins interval until complete recovery. From time of intrathecal injection every 1 minute for the first 5 min, then at 5-min intervals for next 30 minutes and at every 30 minutes intervals until complete resolution of motor anesthesia.

Secondary

MeasureTime frame
to compare effects of dexmedetomidine and clonidine on hemodynamic parameters, sedation and adverse effects. Timepoint: Before spinal anaesthesia, after spinal anaesthesia every 2 minutes for first 10 minutes, then every 5 minutes for 30 minutes, thereafter every 10 minutes till end of surgery . Immediate post operative period, every 2 hours for 6 hours, 12 hours and 24 hours

Countries

India

Contacts

Public ContactDr Samudyatha T J

Bangalore Medical College and Research Institute

drsamudyatha@gmail.com9686216626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026