Comparison of sensory and motor effects of two different medicines Dexamethasone and Magnesium sulfate as adjuvat to Hyperbaric Ropivacaine in spinal anaesthesia for Lowerlimb orthopedic surgeries.

Comparison of Dexamethasone versus Magnesium sulphate as adjuvant to intrathecal Hyperbaric Ropivacaine for lower limb orthopedic surgeries: A Prospective Randomized study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064766

Enrollment

Registered

2024-03-26

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison of Dexamethasone versus Magnesium sulphate as adjuvant to intrathecal Hyperbaric Ropivacaine for lower limb orthopedic surgeries: giving two different adjuvant dexamethasone

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 AND 2

Exclusion criteria

Exclusion criteria: Contraindications to spinal anaesthesia. Allergy or intolerance to local anaesthetics. Local skin infections. History of long term steroid therapy.

Design outcomes

Primary

Measure	Time frame
1.To record and compare the onset of sensory and motor block. 2.To record and compare the duration of sensory and motor block. Timepoint: 1.To evaluate the Onset of sensory and motor blocks every one minute for 5 minutes or till the desired level of block (T10) will be achieved 2. To evaluate the Duration of sensory and motor blocks every 1hr till 4hr after completion of surgery	—

Secondary

Measure	Time frame
1. To record and compare postoperative pain by Visual Analogue Scale (VAS) for 24 hours. 2. To compare time of first rescue analgesia. 3. To compare total analgesic consumption in 24 hr post operatively. 4.To record hemodynamic parameters. 5. To record any complications (post-operative shivering, nausea, vomiting, hypotension ,bradycardia.) Timepoint: 1. VAS postoperatively every 1 hrly for 4 hr then every 4 hrly till 24 hr 2. hemodynamic parameters to be record every 5 min till 15 min then every 15 min till 1 hr then every 1 hrly for 4 hr and after that every 4 hrly till 24 hr	—

Measure

Time frame

1. To record and compare postoperative pain by Visual Analogue Scale (VAS) for 24 hours. 2. To compare time of first rescue analgesia. 3. To compare total analgesic consumption in 24 hr post operatively. 4.To record hemodynamic parameters. 5. To record any complications (post-operative shivering, nausea, vomiting, hypotension ,bradycardia.) Timepoint: 1. VAS postoperatively every 1 hrly for 4 hr then every 4 hrly till 24 hr 2. hemodynamic parameters to be record every 5 min till 15 min then every 15 min till 1 hr then every 1 hrly for 4 hr and after that every 4 hrly till 24 hr

—

Countries

India

Contacts

Public ContactDr Trivedi Viral

Teerthanker Mahaveer Medical College and research center, Moradabad, Uttar pradesh

drtaquifakhri@gmail.com8587003599

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026