In infertile patient ovulation induction is done by using hormones (clomiphene citrate) compared with hormones with gonodotrpins( used for enhancement of ovulation) and proceeds with artificial insemination.

“Comparison of clomiphene citrate with clomiphene citrate and gonadotropins in women with unexplained infertility undergoing intrauterine insemination – A Randomized control trial - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064725

Enrollment

Registered

2024-03-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 1- Obstetrics

Interventions

Intervention1: CLOMIPHENE CITRATE AMD GONODOTROPINS: patients will receive Clomiphene citrate 100 mg from day 3 of the menstrual cycle for 5 days followed by human menopausal gonadotropins (HMG) 75 IU

Eligibility

Inclusion criteria

Inclusion criteria: Age between 18 – 40 years - Unexplained infertility for more than 2 years - Normal ovulation proved by mid luteal serum progesterone level >5 ng/ml, - Patent fallopian tubes confirmed by hysterosalpingography or laparoscopy or saline infusion sonography - Normal semen analysis according to the modified World Health Organization (WHO) criteria - Normal hormonal profile (FSH, LH, prolactin and TSH) in the early follicular phase.

Exclusion criteria

Exclusion criteria: Age >40 years - Any cause of infertility male factor, tubal or ovaria - Any contraindication for used drugs - Women with co-morbidities

Design outcomes

Primary

Measure	Time frame
The primary outcomes will be the number and size of follicles in each ovaryTimepoint: 8 DAYS	—

Secondary

Measure	Time frame
THE SECONDARY OUTCOME WILL BE POSITIVE PREGNANCY TESTTimepoint: 1 MONTH	—

Countries

India

Contacts

Public ContactDrJayasree

sri manakula vianayagar medical college

obg.jayasreem@smvmch.ac.in9443769196

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026