To compare the degree of patient comfort during propofol injection using dexmedetomidine and dexmedetomidine with lignocaine injection.

"A double blinded randomized control trial to compare the effectiveness of dexmedetomidine and combination of dexmedetomidine with lignocaine to alleviate pain on propofol injection."

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064715

Enrollment

Registered

2024-03-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Preservative free lignocaine 2%.: Patients will receive 1.5 ml Preservative free lignocaine 2%. Control Intervention1: dexmedetomidine: dexmedetomidine 0.5 mcg/Kg would be administered

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS WILLING TO PARTICIPATE IN STUDY

Exclusion criteria

Exclusion criteria: PATIENT NOT WILLING TO PARICIPATE IN STUDY PATIENT WITH LIVER DISEASE PATIENT WITH HISTORY OF OPIOID DEPENDENCE

Design outcomes

Primary

Measure	Time frame
TO COMPARE THE EFFECTIVENESS OF DEXMEDETOMIDINE AND DEXMEDETOMIDINE-LIGNOCAINE COMBINATION IN PREVENTING PAIN ON PROPOFOL INJECTION.Timepoint: 8 WEEKS	—

Secondary

Measure	Time frame
TO ASSESS THE EFFECTIVENESS OF STUDY DRUGS IN SUPPRESSION OF PRESSOR RESPONSE DURING LARYNGOSCOPYTimepoint: 8 WEEKS	—

Countries

India

Contacts

Public ContactDr Abhinav Srivastav

Shri.Bhausaheb Hire Government Medical College,Dhule

srivastavabhinav95@gmail.com9810731983

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026