Comparing between two drugs one sedative and another pain relieving drug for giving anaesthesia in lower abdominal surgeries

Comparing the effects of dexmedetomidine versus morphine as adjuvant to 0.5% levobupivacaine for spinal anaesthesia in lower abdominal surgeries - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064710

Enrollment

100

Registered

2024-03-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison between alpha 2 agonist drug and opioid: Comparing between dexmedetomidine 5 micrograms and morphine 100 micrograms with 0.5% levobupivacaine 3 millilitre intrathecally in lo

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade I and 2. 2. Age between 18 to 60 years. 3.Elective lower abdominal surgeries. 4. Patient giving valid informed consent.

Exclusion criteria

Exclusion criteria: 1. Patient refusal 2. Age less than 18 years and more than 60 years 3. ASA grade 3 and 4 4. Patients posted for emergency surgeries 5. Patient with local infection at puncturing site 6. Patients with ischaemic and rheumatic heart disease 7. Patients with coagulation defects and patients on anticoagulants 8. Patients allergic to local anesthetic drugs. 9. Patients with neuromuscular disorders

Design outcomes

Primary

Measure	Time frame
The time for first rescue analgesia after the spinal anaesthesia will be prolonged.Timepoint: 24 hours	—

Secondary

Measure	Time frame
Total dose of rescue analgesia required in 24 h post-operatively will be reduced.Timepoint: 24 hours	—

Countries

India

Contacts

Public ContactDr L Nandhini

Vinayaka Missions Kirupananda Variyar Medical College and Hospitals

naveenasen@gmail.com9486198407

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026