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Study to assess patient response to placing a tube in windpipe after inhaling two different drugs

comparison of intubating conditions following dexmeditomedine versus midazolam nebulization during awake fiberoptic bronchoscope assisted intubation - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064706
Enrollment
20
Registered
2024-03-22
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: One group of patients will receive dexmedetomidine 1mcg/kg body weight by nebulization, 10 minutes before fiberoptic intubation Control Intervention1: Midazolam: One gr

Sponsors

Amrita Institute of medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.surgical patients with difficult airway requiring awake fiberoptic intubation. 2.male and female 3.Aged 18 to 70 years 4.American society of Anaesthesiologists (ASA)physical status 1 to 3

Exclusion criteria

Exclusion criteria: 1. patients with coagulopathies 2.on beta blockers 3.upper airway tumors 4.allergy to test drugs

Design outcomes

Primary

MeasureTime frame
To compare patient comfort as reflected by patient reaction during awake fiberoptic bronchoscope assisted intubation following dexmedetomidine vs. midazolam nebulization in patients with predicted difficult airwayTimepoint: At end of intubation

Secondary

MeasureTime frame
Comparison of ease of intubation process, degree of patient's alertness/sedation, incidence of hypoxia and hemodynamic changes during awake fiberoptic bronchoscope assisted intubations following dexmedetomidine versus midazolam nebulizationTimepoint: At end of intubation

Countries

India

Contacts

Public ContactSujin S

Amrita Institute of Medical sciences ,kochi

suneil71@gmail.com04842856162

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026