Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group A: Dexmedetomidine is used as an adjuvant to propofol-based TIVA: Propofol consumption will be measured till the end of the surgery
Control Intervention1: Group B: Fentanyl is use
Sponsors
ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients between 18-70 years of age including all genders. 2. American Society of Anaesthesiologists Physical status I to III. 3. Scheduled for elective craniotomy for supratentorial brain tumors under general anaesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients refusing to give consent. 2. Patient with body mass index = 35 kg/m². 3. Pregnant patients. 4. Patients allergic to any of the study drugs. 5. Preoperative GCS less than 13. 6. Patients with bleeding diathesis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the mean propofol consumption at the end of the surgery (in mcg/kg/min) in all the patients.Timepoint: At the end of the surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the intra-operative hemodynamic profile between the two groups.Timepoint: At 5-minute intervals till 15 minutes after induction, followed by every 30 minutes till the end of the surgery | — |
Countries
India
Contacts
Public ContactDr Anju Grewal
All India Institute of Medical Sciences Bathinda
Outcome results
None listed