To compare the difference between fixed and increased positive end expiratory pressure on lung compliance in adults patients undergoing surgery under general anaesthesia.

Effect of fixed versus incremental positive end expiratory pressure on intraoperative lung compliance in adult patients undergoing surgery under general anaesthesia : A randomized controlled trial - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064676

Enrollment

Registered

2024-03-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C179- Malignant neoplasm of small intestine, unspecified

Interventions

Intervention1: Group B-Incremental PEEP: Incremental PEEP of 5,7,9cm H2O will be applied at every 15min interval and static lung compliance will be calculated at each step. Control Intervention1: Grou

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing surgery under general anaesthesia with an anticipated surgical duration =120minutes. 2. Adult patients aged between 18-65years. 3. ASA physical status I to III patients.

Exclusion criteria

Exclusion criteria: 1. Patient refusal of consent. 2. Patients with history of any lung pathology. 3. Patients undergoing neurosurgeries 4. Pregnant patients. 5. Patients already on mechanical ventilation.

Design outcomes

Primary

Measure	Time frame
To compare the difference between fixed and incremental PEEP on intraoperative static lung compliance in adult patients undergoing surgery under general anaesthesiaTimepoint: Static lung compliance will be calculated at 3 time points at every 15minutes starting from induction.	—

Secondary

Measure	Time frame
To evaluate immediate post operative pulmonary complications assessed by ultrasonography in adult patients undergoing surgery under general anaesthesia with fixed or incremental PEEP.Timepoint: At two time points:1 hour after extubation and 24 hours after extubation.	—

Countries

India

Contacts

Public ContactDr Gopal Krishan Jalwal

All India Institute of Medical Sciences ,Bathinda

doctorjyotisharma@yahoo.in9968583915

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026