A comparative clinical trial to study the effects of two ayurvedic medicines, simple distillation of plant Prishniparni and Chitraka haritaki rasayana along modern treatment in patients of Chronic Heart Failure.

Evaluating clinical efficacy of Prishniparni Arka (Simple distillation of Uraria picta Desv) and Chitraka Haritaki Rasayana in the management of Chronic Heart Failure - An exploratory clinical trial - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064622

Enrollment

Registered

2024-03-21

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I501- Left ventricular failure, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age: above 21 years and below 60years. 2.Gender: both male and female 3.Diagnosed case of CHF: NYHA function classification II - III/ Stage C HF – according to AHA 4.LVEF 5.Raised Pro-BNP (above normal for the given age) 6.Willingness for participation in the study

Exclusion criteria

Exclusion criteria: 1.Primary organic valvular disease and severe CAD needs surgical intervention. 2.Pulmonary hypertension (PAP > 25mmHg) 3.History of CABG - PTCA - PCI or any other cardiac surgical intervention. 4.Patients having active infective cardiac disease 5.Any evidence of thrombo-embolic heart disease or peripheral arterial disease (Ankle-Brachial index >1.4) 6.Any history of CVA - TIA - DVT or pulmonary embolism in the past 6 months. 7.Pregnant or lactating women. 8.non-willingness to take Ayurvedic medicine.

Design outcomes

Primary

Measure	Time frame
•Changes in Cardiac Biomarker & Ventricular Ejection Fraction Timepoint: day 1 day 75	—

Secondary

Measure	Time frame
• Exercise tolerance capacity (6minute walking distance change - 6MWT) • Changes in Cardiac Function Grading (New York Cardiac Function Grading NYHA) • Changes in health-related quality of life (CHF related quality of life) Timepoint: day 1 day 15 day 30 day 45 day 60 day 75	—

Countries

India

Contacts

Public ContactDr Divya Kajaria

All India Institute of Ayurveda

divyakajaria@gmail.com8826167515

Outcome results