Comparison between two heart immobilising agents in patients undergoing heart surgery.

Comparison of Myocardial protection between Adenosine-Lignocaine-Magnesium Polarising Cardioplegia and St. Thomas Cardioplegia in Routine Elective Adult Cardiac Surgery: Randomised Double Blinded Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064618

Enrollment

120

Registered

2024-03-21

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I089- Rheumatic multiple valve disease,unspecified

Interventions

Intervention1: Adenosine Lignocaine Magnesium Cardioplegia: Cardioplegic solution for open heart surgery at a dose of 20 ml/kg body weight through cardioplegic cannula Control Intervention1: St. Thoma

Eligibility

Inclusion criteria

Inclusion criteria: patients undergoing open heart surgery under Cardiopulmonary bypass

Exclusion criteria

Exclusion criteria: Patient refusal Patients below age of 18 years Congenital Cyanotic heart disease Emergency surgery

Design outcomes

Primary

Measure	Time frame
Improved Ejection fractionTimepoint: 1 hour after weaning from CPB	—

Secondary

Measure	Time frame
Wall motion score index Blood lactate level Vasoactive-inotropic score (VISmax)Timepoint: Wall motion score index pre-CPB, 1 hour after weaning from CPB Blood lactate level pre-CPB, 1 hour after weaning from CPB then every 6 hourly up to 24 hours Vasoactive-inotropic score (VISmax) assessed at first 24 h of surgery	—

Countries

India

Contacts

Public ContactDr Sandeep Kumar Kar

IPGMER and SSKM Hospital

sndpkar@yahoo.co.in9477234900

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026