Health Condition 1: O998- Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: Autologous platelet rich plasma: Intrauterine infusion of 1 ml of autologous platelet rich plasma will be performed with intrauterine insemination catheter under USG guidance. Endometri
Sponsors
Datta megha institute of higher education and research
Eligibility
Inclusion criteria
Inclusion criteria: women aged 18 to 45 years, thin endometrium less than 7 mm on the day of HCG injection, no contraindications for Platelet rich plasma (PRP) and Granulocyte colony stimulating factor(G-CSF) treatment, Women with a normal transvaginal ultrasound and no evidence of a clinically significant abnormality in the uterus or adnexa, Negative CBNAAT, negative AFB staining & negative TBPCR for genital tuberculosis.
Exclusion criteria
Exclusion criteria: patients with a body mass index more than 30 kg/m2, Positive history of intrauterine synechiae, repeated curettage, endometrial injury, Distorted endometrium cavity, submucosal fibroids, endometrial polyps, severe endometriosis, adenomyosis, pelvic cancer and uterine anomalies, chromosomal abnormalities in couples, patients with abnormal liver and kidney function, abnormal thyroid function, immune disorders, hematological disorders;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| expansion of endometrial thickness (EMT)Timepoint: AT BASELINE, AFTER 10 DAYS, AFTER 12 DAYS, AFTER 14 DAYS , AFTER 16 DAYS | — |
Secondary
| Measure | Time frame |
|---|---|
| positive beta-hCG level ? implantation rate (IR), ? positive urine pregnancy test ? clinical pregnancy rate (CPR) by confirmation of Gestational sac with cardiac activity in Trans-vaginal sonography (TVS) ? live birth rate (LBR) (if possible within study periodTimepoint: 2 year | — |
Countries
India
Contacts
Public ContactDr. Smruti Mapari
Datta Meghe Institute Of Higher Education and Research
Outcome results
None listed