Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Granisetron: Single dose of IV infusion of Granisetron 40mcg/kg
Control Intervention1: Palonosetron: Single dose IV infusion 0 of Palonosetron 0.075mg
Sponsors
Dr. Priyanka Prasannan
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA Physical status I and II. 2. Elective Laparoscopic surgeries requiring general anaesthesia with endotracheal intubation and controlled ventilation. 3. Patients willing to give informed consent.
Exclusion criteria
Exclusion criteria: 1. ASA Physical status III and IV. 2. Patients with emetic episodes in the 24 hours prior to surgery. 3. Pregnancy or lactating mothers. 4. Emergency surgeries. 5. Patients with history of smoking or PONV or motion sickness. 6. Patients on medications that cause QT. Prolongation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomitingTimepoint: 0-2 hours, 2-6 hours, 6-24 hours, 24-48 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Post-operative vitalsTimepoint: 30mins,60mins,90 mins,120 mins,3rd hour,4th hour,5th hour,6th hour,8th hour,12th hour,16th hour,20th hour,24th hour,28th hour,32nd hour,36th hour,40th hour,44th hour,48th hour | — |
Countries
India
Contacts
Public ContactDr Ramesh Kumar P B
BGS Global Institute of Medical Sciences
Outcome results
None listed