Supervision of exercises for improving compliance and reducing the side effects of prostate cancer treatment

Optimising adHERence with A Customised flexibLE multimodal exerciSe regimen in prostate cancer patients on radiation and androgen deprivation therapy - a substudy of HERACLES on adherence - (HERACLES-A)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064558

Enrollment

Registered

2024-03-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C61- Malignant neoplasm of prostate

Interventions

Intervention1: A semi-supervised flexible multimodal exercise regimen: The patients randomised to the study arm will meet with the physiotherapy team for advice regarding exercise regimen to be follow

Eligibility

Inclusion criteria

Inclusion criteria: Participants must have all of the following: 1 Confirmed prostatic carcinoma 2 Will undergo radiation therapy - radical 3 radiation therapy or prostate directed radiation therapy 4 Is on androgen deprivation therapy with either medical or surgical methods and is planned to be on this for a minimum duration of 6 months 5 ECOG Performance status 0-1 6 Signed study specific consent form 7 Patient willing and reliable for follow-up

Exclusion criteria

Exclusion criteria: 1.ECOG Performance status 2 or more 2.Limitation in mobility and/or comorbidities that will prevent them from complying to exercise requirements 3.Unable to follow up or poor logistic or social support 4.Deemed to be at high risk of harm due to the presence of lytic bone metastases

Design outcomes

Primary

Measure	Time frame
To assess whether the prescription of an exercise regimen as part of the treatment and offering a semi-supervised flexible multimodal exercise regimen to prostate cancer patients undergoing androgen deprivation therapy and radiation therapy results in better adherence to the exercise regimen at 24 weeks from the start of androgen deprivation therapy taking adherence as 85 %o fthe prescribed exercises Timepoint: at 12 weeks and 24 weeks and 36 week after start of androgen depravation therapy.	—

Measure

Time frame

To assess whether the prescription of an exercise regimen as part of the treatment and offering a semi-supervised flexible multimodal exercise regimen to prostate cancer patients undergoing androgen deprivation therapy and radiation therapy results in better adherence to the exercise regimen at 24 weeks from the start of androgen deprivation therapy taking adherence as 85 %o fthe prescribed exercises Timepoint: at 12 weeks and 24 weeks and 36 week after start of androgen depravation therapy.

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Secondary

Measure	Time frame
To assess whether the prescription of an exercise regimen as part of the treatment and offering a semi-supervised flexible multimodal exercise regimen to prostate cancer patients undergoing androgen deprivation therapy and radiation therapy results in better adherence to the exercise regimen at 24 weeks from the start of androgen deprivation therapy. Timepoint: at 12 weeks and 24 weeks after start of androgen depravation therapy.	—

Measure

Time frame

To assess whether the prescription of an exercise regimen as part of the treatment and offering a semi-supervised flexible multimodal exercise regimen to prostate cancer patients undergoing androgen deprivation therapy and radiation therapy results in better adherence to the exercise regimen at 24 weeks from the start of androgen deprivation therapy. Timepoint: at 12 weeks and 24 weeks after start of androgen depravation therapy.

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Countries

India

Contacts

Public ContactTata medical center kolkata

Tata medical center,kolkata

85moses@gmail.com9007395797

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026