A study to compare the effect of two drugs used for giving spinal anaesthesia to perform surgeries below the level of umbilicus.

Comparison of clinical efficacy of hyperbaric levo-bupivacaine (0.5%) with hyperbaric ropivacaine(0.75%) in infraumbilical surgeries under spinal anaesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064520

Enrollment

Registered

2024-03-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: V039- Pedestrian injured in collision with car, pick-up truck or van, unspecified whether traffic or nontraffic accident

Interventions

Intervention1: Hyperbaric levo bupivacaine (0.5%) , Hyperbaric ropivacaine(0.75%).: I will administer two different drugs that is 3ml of 0.5% hyperbaric bupivacaine and 3ml of 0.75% hyperbaric ropivac

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1 and Grade 2 patients posted for infraumbilical surgeries.

Exclusion criteria

Exclusion criteria: Age less than 18 years and more than 60 years. ASA Grade 3 and above patients. Patient allergic to the interventional drugs. Patient not willing to participate in the research. Patient having any neurological disease linked with brain and spinal cord.

Design outcomes

Primary

Measure	Time frame
Assessing the time of onset of sensory blockade and time of onset of motor blockade after subarachnoid injection of the study drugs (hyperbaric levo-bupivacaine and hyperbaric ropivacaine) and comparing the data.Timepoint: At one minute interval after administation of study drugs till 20 minutes.	—

Secondary

Measure	Time frame
Assessment of the time required for two segments regression & complete regression of sensory blockade & complete regression of motor blockade in the two groups receiving the study drugs & time of first rescue analgesia requirement in the two groups will be done. Haemodynamic variations caused by the study drugs in the two groups will be noted. The quality of post operative analgesia in the two groups will be assessed & any adverse effects caused by the study drugs in the two groups will be noted. Data will be collected & compared. Timepoint: At baseline , 2 min interval till 10 minutes & then at 15 minutes interval till completion of surgery & postoperative period till patient complains of pain.	—

Measure

Time frame

Assessment of the time required for two segments regression & complete regression of sensory blockade & complete regression of motor blockade in the two groups receiving the study drugs & time of first rescue analgesia requirement in the two groups will be done. Haemodynamic variations caused by the study drugs in the two groups will be noted. The quality of post operative analgesia in the two groups will be assessed & any adverse effects caused by the study drugs in the two groups will be noted. Data will be collected & compared. Timepoint: At baseline , 2 min interval till 10 minutes & then at 15 minutes interval till completion of surgery & postoperative period till patient complains of pain.

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Countries

India

Contacts

Public ContactDr Manoj Panchal

Pandit BD Sharma PGIMS Rohtak

susheelataxak@gmail.com9896067416

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026