Study on dose requirement of dexmedetomidine with the use of Bispectral Index Monitoring

Impact of bispectral index monitoring on dose requirement of dexmedetomidine during total parotidectomy under general anesthesia without use of muscle relaxants. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064505

Enrollment

Registered

2024-03-20

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Bispectral Index Monitoring: In one group of patients the dose of dexemedetomidine will be adjusted with bispectral index monitoring throughout period of surgery Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: -American Society of Anesthesiologists physical status (ASA PS) 2 to 3, -Patients undergoing total parotidectomy with nerve conduction studies

Exclusion criteria

Exclusion criteria: -Patients with basal HR less than sixty per min, -beta blockers, -heart blocks, -hypersensitivity to dexmedetomidine -nasal intubation or fibreoptic intubation

Design outcomes

Primary

Measure	Time frame
To compare the intraoperative dexmedetomidine infusion dose requirement with and without bispectral index (BIS) monitoring in patients undergoing total parotidectomy under general anesthesia without use of muscle relaxants.Timepoint: End of surgery	—

Secondary

Measure	Time frame
To compare intraoperative patient immobility, hemodynamic responses, sevoflurane & propofol consumption, need for intervention if patient moves, incidence of hypotension, use of vasopressors & time taken for extubation in both groups.Timepoint: patient immobility will be assessed at end of surgery, hemodynamic responses will be assessed every half hourly during surgery, sevoflurane & propofol consumption will be noted at the end of surgery, & the time taken for extubation will be documented at the end of surgery.	—

Measure

Time frame

To compare intraoperative patient immobility, hemodynamic responses, sevoflurane & propofol consumption, need for intervention if patient moves, incidence of hypotension, use of vasopressors & time taken for extubation in both groups.Timepoint: patient immobility will be assessed at end of surgery, hemodynamic responses will be assessed every half hourly during surgery, sevoflurane & propofol consumption will be noted at the end of surgery, & the time taken for extubation will be documented at the end of surgery.

—

Countries

India

Contacts

Public ContactMaharnab Bhuyan

Amrita Institute of Medical Sciences, Kochi

lakshmi.k.238@gmail.com04842856162

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026