Health Condition 1: F23- Brief psychotic disorder Health Condition 2: F202- Catatonic schizophrenia Health Condition 3: F22- Delusional disorders Health Condition 4: F201- Disorganized schizophrenia Health Condition 5: F28- Other psychotic disorder not due to a substance or known physiological condition Health Condition 6: F208- Other schizophrenia Health Condition 7: F200- Paranoid schizophrenia Health Condition 8: F205- Residual schizophrenia Health Condition 9: F205- Residual schizophrenia He
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
Medical Research Council
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for people with psychosis (“cases ?): 1. Age 18 to 64 years at the start of the case-finding period 2. Currently resident in catchment area (primary residence) 3. Presence of ICD-11 psychotic disorder, including substance-induced psychoses. 4. Not treated with antipsychotic medication for more than one continuous month prior to the start of initial case identification Inclusion criteria for relatives: 1. Age 18 and above 2. Relative of an individual with a psychotic disorder who has consented to participate in the current study (either first-degree relative or other family member involved in care of the participating individual) Inclusion criteria for controls: 1. Age 18 to 64 years 2. Resident in catchment area (primary residence)
Exclusion criteria
Exclusion criteria: Exclusion criteria for people with psychosis (“cases ?): 1. Transient psychotic symptoms resulting from acute intoxication as defined by ICD- 11 2. Moderate or severe learning disability, as defined by ICD-11 3. Clinically manifest organic cerebral disorder (e.g. infections, parasitic, toxic, cerebrovascular, epilepsy, brain injury), as defined by ICD-11 Exclusion criteria for relatives: 1. Insufficient contact with case to provide information on family burden or psychiatric history Exclusion criteria for controls: 1. Past or current ICD-10 psychotic disorder 2. Transient psychotic symptoms due to acute intoxication as defined by ICD-11 3. Moderate or severe learning disability, as defined by ICD-11 4. Clinically manifest organic cerebral disorder (e.g. infections, parasitic, toxic, cerebrovascular, epilepsy, brain injury), as defined by ICD-11 5. Related to the matched case
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Predictors of medium term course and outcome of psychoses; psychopathology; living situations; physical health; interpersonal relationships Stress Sensitivity; Mood and Behaviour Cognitive Functioning Accelerated Aging Timepoint: 2 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Pathways to homelessness; Help-seeking behaviourTimepoint: 2 year | — |
Countries
India, Nigeria, Trinidad and Tobago
Contacts
Public ContactDr Thara Rangaswamy
Schizophrenia Research Foundation, India
Outcome results
None listed