A comparison of two medicines added to the regular medicine in producing numbness of the lower half of the body for surgeries

Intrathecal dexmedetomidine versus nalbuphine as adjuvant to levobupivacaine among patients undergoing infraumblical surgeries in tertiary care hospital - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064440

Enrollment

Registered

2024-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Patients will be administered dexmedetomidine 5mcg along with 0.5% hyperbaric levobupivacaine for spinal anaesthesia . Route- intra- thecal, frequency of administratio

Eligibility

Inclusion criteria

Inclusion criteria: All elective infraumblical surgeries ASA grade 1 and 2

Exclusion criteria

Exclusion criteria: Patient refusal History of allergy to study drugs Local site infection History of spinal surgeries, spinal deformities Coagulopathy Dysrhythmia BMI more than 35 Height less than 150 cm

Design outcomes

Primary

Measure	Time frame
onset of sensory and motor block , Duration of sensory and motor blockTimepoint: 1. Time of administration of drug 2. Onset of sensory block 3. Onset of motor block 4. Time of regression of sensory block to T10 5. Time of recovery of motor block to modified bromage scale 2	—

Secondary

Measure	Time frame
Duration of analgesiaTimepoint: Time of administration of first dose of rescue analgesia	—

Countries

India

Contacts

Public ContactVidhya N

Sree balaji medical College and hospital

drvidhya.subramanian@gmail.com9597836540

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026