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Effect of general anaesthesia versus brachial plexus block on neutrophil count, neutrophil to lymphocyte ratio, and platelet to lymphocyte ratio in patients undergoing upper limb fracture surgery

Effect of General Anaesthesia Versus Brachial Plexus Block on Neutrophil count, Neutrophil to Lymphocyte Ratio, and Platelet to Lymphocyte Ratio in Patients Undergoing Upper Limb Fracture Surgeries: A Randomized Clinical Study - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064439
Enrollment
50
Registered
2024-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S424- Fracture of lower end of humerus Health Condition 2: S525- Fracture of lower end of radius Health Condition 3: S526- Fracture of lower end of ulna Health Condition 4: S423- Fracture of shaft of humerus Health Condition 5: S523- Fracture of shaft of radius Health Condition 6: S522- Fracture of shaft of ulna Health Condition 7: S422- Fracture of upper end of humerus Health Condition 8: S521- Fracture of upper end of radius Health Condition 9: S520- Fracture of upper end o

Interventions

Intervention1: Blood sampling and Complete blood count: Neutrophil count, neutrophil to lymphocyte ratio and platelet to lymphocyte ratio Total duration 24 hours Control Intervention1: Effect of gener

Sponsors

Uttar Pradesh university of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1). Body mass index 18.5- 24.9 kg/m2 2). American society of anaesthesiologists (ASA) physical status I and II 5). Patients scheduled for upper limb fracture surgeries

Exclusion criteria

Exclusion criteria: 1). Patients/attendant refusal 2). Patient having an infection at the surgical site 3). Patient on chronic treatment with steroid or immunosuppressants 4). Patient on recent chemotherapy 5). Patient hepatic and renal dysfunction 6). Surgery duration >180 minutes 7). Patient converted to general anaesthesia due to brachial plexus block failure 8). Patients with pre operative abnormal leukocytes count, neutrophil count, lymphocyte count and platelet count

Design outcomes

Primary

MeasureTime frame
Effect of general anaesthesia versus brachial plexus block on neutrophil to lymphocyte ratio Effect of general anaesthesia versus brachial plexus block on neutrophil count Effect of general anaesthesia versus brachial plexus block on platelet to lymphocyte ratioTimepoint: Pre op Just after surgery 4 hour after surgery 24 hour after surgery

Secondary

MeasureTime frame
Effect of general anaesthesia versus brachial plexus block on neutrophil countTimepoint: Pre op Just after surgery 4 hour after surgery 24 hour after surgery;Effect of general anaesthesia versus brachial plexus block on platelet to lymphocyte ratioTimepoint: Pre op Just after surgery 4 hour after surgery 24 hour after surgery

Countries

India

Contacts

Public ContactDr.Abhishek Kasaudhan

UTTAR PRADESH UNIVERSITY OF MEDICAL SCIENCES

ushashukla1970@gmail.com9412201915

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026