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probing of nasolacrimal duct and irrigation with Mitomycin-C in adults with primary acquired nasolacrimal duct obstruction: is it effective?

To assess the efficacy and safety of probing of nasolacrimal duct with Mitomycin-C in adults with primary acquired nasolacrimal duct obstruction. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/03/064417
Enrollment
40
Registered
2024-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H045- Stenosis and insufficiency of lacrimal passages

Interventions

Intervention1: mitomycin c: probing of nasolacrimal duct will be done in all cases. 1. followed by irrigation with 1ml of mitomycon c 0.02% solution in case group 2. normal saline irrigation in contro

Sponsors

Dr Vandana Sharma
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients having a history of primary epiphora due to NLDO patients who will give written consent for the procedure.

Exclusion criteria

Exclusion criteria: • Patient with history of previous trauma, recurrent dacryocystitis, surgery, any other obvious cause for NLDO. • Any ocular disease leading to hyper-lacrimation such as dry eye, corneal ulcer, ocular foreign bodies, etc. • Pregnant women and women who will be planning to become pregnant within the next 6 months.

Design outcomes

Primary

MeasureTime frame
improvement in Kraft Crawford scale score of watering of eye and patency of lacrimal duct on syringingTimepoint: 1 week 1 month 3 months—

Secondary

MeasureTime frame
N/ATimepoint: N/A—

Countries

India

Contacts

Public ContactDr Vandana Sharma

AIIMS Bathinda

dr_vandana_9@yahoo.in9463671706

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026