A clinical study to find if there any difference in the outcomes between the SINGLE VS TWO STEP t- PRK with respect to visual outcomes. And to study rate of corneal wound healing with different lubricating eye drops.

Transepithelial photorefractive keratectomy : A randomized comparative study between two-step and one-step techniques of transepithelial PRK and the rate of wound healing with different lubricating eye drops.

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2024/03/064395

Enrollment

Registered

2024-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H521- Myopia

Interventions

Intervention1: 1) Transepithelial Photorefractive Keratectomy. 2) Lubricating eye drops: 1) Each person recruited into the study will undergo the two- step transepithelial phototherapeutic keratectom

Eligibility

Inclusion criteria

Inclusion criteria: 1)People who have myopic astigmatism with a spherical error between -1 to -6 diopters and a cylindrical error between -0.5 to -4 diopters. 2)People who have a stable refractive error at least for the past 1 year. 3)People who can come for a followup duration of at least 1 month. 4)Normal corneal tomography. 5)Minimum pachymetry of 470 micrometers.

Exclusion criteria

Exclusion criteria: 1)History of any previous corneal surgery. 2)Family history of keratoconus. 3)History of keloid tendency. 4)Pregnant,lactating women( upto 6 months of delivery). 5)If the person has keratitis or corneal scar. 6)Any corneal dystrophies. 7)Hyperopia.

Design outcomes

Primary

Measure	Time frame
visual acuity rate of corneal epithelial wound healingTimepoint: visual acuity on 1 and 3 months rate of corneal epithelial wound healing on days 1,3,5 and 1 month	—

Secondary

Measure	Time frame
Pain & discomfort in eyes after surgery( t- PRK). Timepoint: Pain & discomfort in eyes after surgery( t- PRK) on days 1, 3, 5 & at 1 month.	—

Countries

India

Contacts

Public ContactGanthi Chetana Lakshmi

Sankara eye hospital, Pedakakani, Guntur

sudhakar@sankaraeye.com9705190929

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026