Health Condition 1: F330- Major depressive disorder, recurrent, mild Health Condition 2: F331- Major depressive disorder, recurrent, moderate Health Condition 3: F320- Major depressive disorder, singleepisode, mild Health Condition 4: F321- Major depressive disorder, singleepisode, moderate
Conditions
Interventions
Intervention1: Individualized homoeopathic medicines in centesimal potencies plus concomitant care: Intervention is planned as administering indicated homoeopathic medicines
in centesimal potencies (
dosage and repetition depending upon the individual requirement of the cases.
Patients will be advised to refrain from handling the globules or from eating, drinking, smoking
or brushing teeth withi
dosage and repetition will be maintained
depending upon the individual requirement of the cases. All sundry items will be procured from
a Good Manufacturing Practice (GMP) certified firm. All the en
Sponsors
D. N. De Homoeopathic Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: A. Elderly people with depression of not less than two weeks duration, with a minimum of two typical and two common symptoms will be included in the study. • Typical symptoms: o Depressed mood o Loss of interest and enjoyment. o Increased fatigability and diminished activity • Common symptoms: o Reduced concentration and attention. o Reduced self-esteem and self-confidence. o Guilt feeling and unworthiness (mild type of episode) o Bleak and pessimistic view of the future. o Disturbed Sleep o Diminished appetite B. Age above 60 years C. Mild and moderate depression [HDRS score - 8-13 mild, 14-18 moderate] D. GDS-15 score more than 5 E. Participants having prior experience or knowledge of the treatment; e.g., primed to expect ‘homoeopathic aggravation’ and available treatment options for the disease conditions, intimated through Patient Information Sheet.
Exclusion criteria
Exclusion criteria: A. Mood disturbance when associated with bipolar affective disorder, schizophrenia, schizophreniform disorder, schizoaffective disorder, or psychotic disorder. B. Severe dementia (MoCA score less than 10) C. Currently receiving any effective anti-depressant. D. Active suicidal E. Uncontrolled systemic disorders. F. Undergoing homoeopathic treatment for any chronic disease within the last six months. G. Vulnerable population- Unconscious, non-ambulatory, too sick for consultation, differently abled, terminally ill or critically ill patients, mentally incompetent people. H. Self-reported immune-compromised state. I. Patients with the habit of tobacco chewing and/or smoking, alcoholism, and/or any other form(s) of substance abuse and/or dependence. J. Simultaneous participation in any other clinical trials K. Not Providing with written informed consent to participate voluntarily
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Rating Scale (HDRS 17)Timepoint: Baseline, every month, up to 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Measure Yourself Medical Outcome Profile-2 (MYMOP-2)Timepoint: Baseline, every month, up to 3 months;Geriatric Depression Scale 15 (GDS-15)Timepoint: Baseline, every month, up to 3 months | — |
Countries
India
Contacts
Public ContactProf Dr Rajat Kumar Pal
D. N. De Homoeopathic Medical College and Hospital
Outcome results
None listed