Abdominal closure after emergency laparotomy

Abdominal Closure after Emergency Laparotomy (ACE) trial: Comparison of Mass closure and Small bites techniques for closure after emergency laparotomy - ACE

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/03/064359

Enrollment

296

Registered

2024-03-18

Start date

Unknown

Completion date

Unknown

Last updated

2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K650- Generalized (acute) peritonitis Health Condition 2: O- Medical and Surgical Health Condition 3: K566- Other and unspecified intestinal obstruction Health Condition 4: K631- Perforation of intestine (nontraumatic) Health Condition 5: K913- Postprocedural intestinal obstruction

Interventions

Intervention1: Small bites closure of abdominal wall: At time of rectus sheath closure after laparotomy, bites are taken from the rectus sheath anterior and posterior layers, excluding the rectus musc

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing emergency laparotomy with a midline abdominal incision

Exclusion criteria

Exclusion criteria: 1. Pregnant women 2. Patients with non midline incision used to open the abdomen 3. Patients undergoing damage control laparotomy

Design outcomes

Primary

Measure	Time frame
Incidence of Incisional Hernia postoperativelyTimepoint: 3 months, 6 months, 12 months, 24 months	—

Secondary

Measure	Time frame
Burst abdomenTimepoint: 3 days, 7 days, 14 days, 28 days post operatively	—

Countries

India

Contacts

Public ContactAkshant

Dr Babasaheb Ambedkar Hospital

akshantp@gmail.com9953558813

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026