Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous Ondansetron before spinal anesthesia: 0.1mg/kg dose of Ondansetron diluted with 0.9% Normal saline (total volume 10ml) is given Intravenously (single dose) 10min prior to sp
Sponsors
Rajendra Institute Of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Patient consent Pregnant females between 18 to 45 years of age posted for elective caeserean section in Rajendra Institute of Medical Sciences
Exclusion criteria
Exclusion criteria: Emesis gravidarum Preeclampsia Morbid obesity Contraindications to spinal anesthesia, allergy or intolerance to local anaesthetic agents or other agents used for the study. Presence of co-morbidities like severe anaemia, uncontrolled diabetes mellitus, asthma, uncontrolled hypertension, severe cardiac disease Patient’s belonging to ASA III and above
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Changes in Systolic blood pressure 2. Changes in diastolic blood pressure 3.Changes in mean arterial pressure 4.Changes in Heart RateTimepoint: 1.From time of induction, every 2 minutes till 20minutes and thereafter every 5minutes till 50minutes. 2.From time of induction, every 2 minutes till 20minutes and thereafter every 5minutes till 50 minutes. 3. From time of induction, every 2 minutes till 20minutes and thereafter every 5minutes till 50minutes. 4.From time of induction, every 2 minutes till 20minutes and thereafter every 5minutes till 50minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Fetal umblical artery pH,lactate,bicarbonate, sodium, potassium, chloride and calcium levels by arterial blood gas analysis. 2. APGAR scoreTimepoint: 1. Immediately after delivery (ideally within 3 minutes) 2. At 1 minute, 3 minute, 5minute and 10minutes post delivery | — |
Countries
India
Contacts
Public ContactDr Ladhu Lakra
Rajendra Institute Of Medical Sciences
Outcome results
None listed